Bioinformatics Tools
生物信息学工具
RNAnano_Designer
An RNA nano-designer for designing lssRNA targeting specific genes and self-assembly folding to RNA nanostructures of triangle, square, pentagon, hexagon and tetrahedron.
//bi.sky.zstu.edu.cn/ssFRND/ 02dsRNA_designer
An effective and specific dsRNA designer for pest RNA interference with off-target analysis against human, bees and other environmental organisms.
https://bi.sky.zstu.edu.cn/dsRNA_design/ 03siRNA_Designer
An effective and specific siRNA designer for pest RNA interference with off-target analysis against human, bees and other environmental organisms.
https://bi.sky.zstu.edu.cn/siRNA_designer/design.html 04Codon_optimizer
Optimize the codon preference of the target gene in Escherichia coli based on the codon usage frequency of the source species.
https://bi.sky.zstu.edu.cn/code_optimized/ 05WJ-RNA_Designer
An RNA nano-designer for designing lssRNA targeting specific genes and self-assembly folding to 3WJ- and 4WJ-RNA nanostructures.
https://bi.sky.zstu.edu.cn/Rnano/index.html 06TCM_detector
A species detector for traditional Chinese medicine based on DNA fingerprinting.
https://bi.sky.zstu.edu.cn/TCM_detector/index.php 07MYCOsiRNA
An effective and specific siRNA designer for fungi and oomycete RNAi based on the assessments of target site accessibility and genome-wide off-target selection.
https://bi.sky.zstu.edu.cn/MYCOsiRNA/index.html 08Batch Primer3 Designer
Batch PCR primer design for multi-FASTA sequences with editable Primer3 constraints, supporting per-sequence primer output and downloadable result tables.
https://bi.sky.zstu.edu.cn/primer3_batch/ 09RNAi BioReport
Registration-oriented bioinformatics report generation for RNAi pesticides with multi-FASTA parsing, dsRNA window recommendation, siRNA pre-screening, and downloadable structured report files.
https://bi.sky.zstu.edu.cn/bio_report/SCI Publications
近三年发表 SCI 学术论文情况
- Sun S, Yan L, Liu Z, Jin W*. Design of Anti-Tumor RNA Nanoparticles and Their Inhibitory Effect on Hep3B Liver Cancer. Biomolecules. 2026; 16(1):45.
- Lu M, Jiang W, Liu Z, Liu Y, Wu F, Jin W*. Development of a Dual Gene-Targeted Multi-Sirna with Branched Structure and Its Role in the Therapy of Liver Cancer. Pharmaceuticals. 2025; 18(12):1844.
- Ya Chen, Yiqing Liu, Yani Huang, Fangli Wu, Weibo Jin*. Development of triangle RNA nanostructure for enhancing RNAi-mediated control of Botrytis cinerea through Spray-Induced Gene Silencing without extra nanocarrier. Biology-basal. 2025-11-13
- Jin WB, Zhang XY, Wu FL*, Zhang PW. Selection of BcTRE1 as an effective RNAi target for dsRNA-Based control of Botrytis cinerea. Physiological and Molecular Plant Pathology. 2025; 139:102773.
- Huang H, Liu X, Liu Y, Wu F, Jin W*. Genome-Wide Identification and Expression Analysis of 1-Aminocyclopropane-1-Carboxylate Synthase (ACS) Gene Family in Myrica rubra. International Journal of Molecular Sciences. 2025; 26(10):4580. https://doi.org/10.3390/ijms26104580
- Zhao, X., Liu, Y., Huang, H., Sun, Y., Wu, F., & Jin, W*. (2024). A Simple and Efficient One-Step Synthesis System for Flexible Production of Circular RNA in E. coli. Biomolecules, 14(11), 1416. https://doi.org/10.3390/biom14111416
- Zhao, X., Liu, Z., Liu, Y., Lu, M., Xu, J., Wu, F., & Jin, W*. Development and application of an RNA nanostructure to induce transient RNAi in difficult transgenic plants. Biotechnology Journal, 2024, 19:e2400024.
- Wu F, Yan L, Zhao X, Lv C, Jin W*. Development of an RNA Nanostructure for Effective Botrytis cinerea Control through Spray-Induced Gene Silencing without an Extra Nanocarrier. Journal of Fungi. 2024; 10(7):483.
- Sun J, Lu S, Xiao J, Xu N, Li Y, Xu J, Deng M, Xuanyuan H, Zhang Y, Wu F, Jin W*, Liu K*. Inhibition of SARS-CoV-2 Replication by Self-Assembled siRNA Nanoparticles Targeting Multiple Highly Conserved Viral Sequences. Viruses. 2024; 16(7):1072.
- Guo K, Huang Z, Wang C, Liu X, Chen Y, Fang J, Jin W, Xu J, Wu F*, Zhou X*. Nematicidal effects of silencing arginine kinase in the pine wood nematode, Bursaphelenchus xylophilus, determined using a dsRNA-like siRNA assembly. Int J Biol Macromol. 2024; 279:135401.
- Wu F, Huang Y, Jiang W and Jin W* (2023) Genome-wide identification and validation of tomato-encoded sRNA as the cross-species antifungal factors targeting the virulence genes of Botrytis cinerea. Front. Plant Sci. 14:1072181.